So if you are one of the user has mcafee antivirus, specially the drive encryption enabled, you will run into issue upgrading Win 10 patches or upgrade. Usually the error pretty similar to below,

So solution would be upgrading OS via mcafee switch enabled via CMD. Here is what I did,
*****Copy Windows update to C: folder called updates( This was 1903 update and I downloaded it as ISO from Microsoft site and then mount and copied to the folder)
******Then bring up CMD as administrator and type cd c:\update, which change the directory.
******Then run this
Setup.exe /ReflectDrivers “%programfiles%\McAfee\Endpoint Encryption\OSUpgrade“
OR
Setup.exe /ReflectDrivers “C:\Program Files\McAfee\Endpoint Encryption\OSUpgrade”
Upgrade should run without and error.
Here is the full KB article link,